| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ebfc8d66ac1303ed1e3e999d65aa236 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-105831
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-08 |
| filingDate |
1994-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c53a894935d48b9bdcc3f90e79f8d9d3 |
| publicationDate |
2002-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1193271-A2 |
| titleOfInvention |
Compositions and methods for protein structural determinations |
| abstract |
A method for determining three-dimensional structuralninformation of a protein involves producing the protein in anform substantially labeled with 13 C or 15 N or both ornsubstantially labeled with 15 N and 13 C and partially labeled withn 2 H and subjecting the protein to nuclear magnetic resonancenspectroscopic analysis. The isotopically labeled protein isnproduced by a method which involves producing a substantiallynlabeled microbial protein hydrolysate, subjecting the proteinnhydrolysate to cation exchange chromatography to produce anpartially purified labeled amino acid mixture, subjecting thenpartially purified labeled amino acid mixture to anion exchangenchromatography to produce a purified labeled amino acid mixturenand supplementing the purified labeled amino acid mixture withnisotopically labeled cysteine and optionally with isotopicallynlabeled glutamine and asparagine. |
| priorityDate |
1993-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |