http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1190720-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcf52764549e50e5dd0de2b178c8cd50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2000-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_642b7761819dd2e9e45f106f542ebd3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_781556d6fdb9a1dc8ca40b4e7008afe3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_013e6bf770dbb98bd2e6ebe538541983 |
| publicationDate | 2004-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1190720-B1 |
| titleOfInvention | Liquid pharmaceutical composition for oral administration of bitter hydrolysis-susceptible active substances |
| abstract | Liquid pharmaceutical composition for the oral administration of active substances that are bitter and susceptible to hydrolysis. The composition (for 100 ml) comprises: 3-15 g of active substance; 0.01-0.3 g of preservative (sorbic acid, methyl p-hydroxybenzoate); sufficient amount of an edible oily vehicle formed by triglycerides of short- or medium-chain acids (caprylic, capric) to make up 100 ml; a suitable quantity of sweetener (sodium saccharin, sodium cyclamate, ammonium glycyrricinate) optionally accompanied by a suitable amount of a flavouring agent (walnut, condensed milk, coconut, banana); 0.5-2 g of soya lecithin; 0.1-5 g of thickener of the type derived from cellulose (N-ethylcellulose); and 0.05-1 g of a polysorbate type surfactant. Optionally it includes 0.5-5 g of mannitol and 1-5 g of sodium bicarbonate. It is useful for the administration of bitter active substances (ciprofloxacin, paracetamol, erythromycin etc.) in children, the elderly and patients who are little motivated. It is stable, easy to ingest and of bearable taste. |
| priorityDate | 1999-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.