abstract |
Novel pyrazolobenzodiazepines having formula (I) and the pharmaceutically acceptable salts thereof, wherein R?1, R2, R3 and R4¿ are as defined herein inhibit cyclin-dependent kinases (CDKs), in particular CDK2, are anti-proliferative agents useful in the treatment or control of cell proliferative disorders, in particular breast, colon, lung and prostate tumors. |