http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1181371-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1238c3b436318163b58ec3f9da98c1f3 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate | 2000-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abf569d5762c6b2727086d079c4845b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80aa1b0db012ada6ef87ee8cc92e6e8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8c713b1832b0c0086bb8f74e7200c83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da4ddcb4dddec6125b99e1e8f30def87 |
publicationDate | 2003-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1181371-B1 |
titleOfInvention | Attenuated mutant enteropathogenic e. coli (epec) strains, process for their production and their use |
abstract | The present invention relates to attenuated mammalian enteropathogenic E. coli (EPEC) strains comprising a deletion of an intimin encoding gene sequence wherein said deletion fully eliminates a functional intimin protein, which can be effectively used for the production of a vaccine against enteropathogenic E. coli (EPEC) infections in mammals. The invention also relates to recombinant vectors to be used in methods for the construction of said to attenuated mammalian enteropathogenic E. coli (EPEC) strains. The invention also relates to a method for in vitro differentiating between field infected and vaccinated individuals wherein said vaccinated individuals have been vaccinated with a vaccine comprising attenuated mammalian enteropathogenic E. coli (EPEC) strains having a deletion of an intimin gene sequence and said field infected infected individuals are in vitro diagnosed on the basis of the presence of intimin antibodies. |
priorityDate | 1999-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 253.