http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1181368-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd7983a5141a8f8de20e1e1b67c10fa7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43563 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate | 2000-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ed309bd37296196bf6aaec1eef7274 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ab8ab0c21755f8d5d19d0c38a009fac |
| publicationDate | 2002-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1181368-A1 |
| titleOfInvention | Muteins of bilin-binding protein |
| abstract | The invention relates to muteins of bilin-binding protein with a binding ability to digoxigenin and the fusion proteins of said muteins, a method for preparing said muteins and fusion proteins thereof and to their utilization for detecting or binding digoxigenin-labeled biomolecules. The invention especially relates to a polypeptide selected from the muteins of the bilin-binding protein, which is characterized in that (a) it can bind digoxigenin or digoxigenin conjugates; (b) it does not bind ouabain, testosterone and 4-aminofluorescein (c) at least one of the sequence positions 28, 31, 34, 35, 36, 37, 58, 60, 69, 88, 90, 95, 97, 114, 116, 125 and 127 of the bilin-binding protein has an aminoacid substitution. Due to their simple molecular structure, the inventive muteins provide advantages for production and utilization in comparison with antibodies against the digoxigenin group. |
| priorityDate | 1999-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 190.