Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c31d756b30e9f6fe84a8d02899191b6c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
2000-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68d584aeec2bfa7c3e0e7e461758ee88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62c774fb6d171b423abb97f6ab7dd72d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac5d6951a9bbef852b05480505dfcf46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ce28b275f685ef9eb0bd4ef7523e706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_953f629e656a5264392ed96bb4b4e41a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f252c98fe05dae647fe4350ce85810b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cdba1aa877f16f3b795e173427a2337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_832c8ec82e123a27039f3d1df29ad649 |
publicationDate |
2007-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1179593-B1 |
titleOfInvention |
Process for producing recombinant insulin from novel fused protein |
abstract |
This invention relates to a DNA encoding a fusion protein of formula (I) ÄYÜ-ÄX1Ü-ÄB-chainÜ-ÄX2Ü-ÄLinkerÜ-ÄX3Ü-ÄA-chainÜ wherein Y is a leader peptide sequence for the expression and secretion of the protein, comprising at least one amino acid residue; X1 is an amino acid sequence which is cleavable enzymatically or chemically; B-chain is the amino acid sequence of insulin B chain; X2 is an amino acid sequence which is cleavable enzymatically; Linker is a linker sequence comprising at least one amino acid residue; X3 is an amino acid sequence which is cleavable enzymatically; and A- chain is the amino acid sequence of insulin A chain, and to a method for producing insulin using an expression system containing the DNA in high efficiency and high yield. |
priorityDate |
1999-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |