| abstract |
This invention relates to novel 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives of formula (I) wherein R1 is C1-C6 alkyl; R2 is hydrogen, C¿1?-C6 alkyl, halo C1-C6 alkyl or phenyl; R?3¿ is hydrogen or halo; and R?4 and R5¿ are independently hydrogen, C¿1?-C6 alkyl or halo C1-C6 alkyl, their pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and the use of such compounds to treat CNS, gastrointestinal and other disorders. |