| abstract |
A method for promoting the binding of a human or animal peroxisome activator-responsive receptor to a target gene sequence and promoting the gene expression in downstream thereof which comprises administering, as peroxisome activator-responsive receptor agonist(s), to humans or animals a preventively or therapeutically effective amount of at least one member selected from among conjugated unsaturated C10-26 fatty acids having a conjugated triene structure (-CH=CH-CH=CH-CH=CH-) or a conjugated tetraene structure (-CH=CH-CH=CH-CH=CH-CH=CH-) in the molecule and salts and ester derivatives thereof. Use of this method makes it possible to reduce visceral fat, to inhibit visceral fat accumulation, to prevent or relieve lipid metabolic error, to prevent or relieve sugar metabolic error, or to prevent or treat cancer in humans or animals. |