http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1169341-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09ca9729ffc31d7114ca1ad545db552d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_231af2ebd4162c6371267a59aef69c0d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-28162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-28121 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-08 |
| filingDate | 2001-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d920089842b10e8aa874d0ac98563954 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_761a4961af340b9ad6aee1e2c896d8b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_381b56dbbe208addabf9d8c31488026e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6699f3faeca709010470475806fccb60 |
| publicationDate | 2002-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1169341-A1 |
| titleOfInvention | Infectious cdna clone of hepatitis e virus (hev) genome, its production and uses |
| abstract | The present invention relates to a unique genetically engineered nucleic acid clone of hepatitis E virus (HEV) which comprises the complete structural (ORF2 and ORF3) and non-stuctural (ORF1) genes, viz. the complete coding sequence, of HEV, flanked by 5` and 3`non-coding regions along with a 3`polyadenylated tail to the 3` non-coding region, said clone being capable of infecting cultured liver cells and replicating, transcribing and assembling HEV therein. The invention also incorporates within its scope a process for synthesising such clone and the expression therefrom of viral proteins adapted for use in the detection of the presence of antibodies to HEV in biological samples. Other uses to which the clone and the expressed viral proteins can be put include a diagnostic test kit for the presence of HEV infection comprising said viral proteins, and HEV vaccine comprising non-infectious HEV particles produced from a mutation of said nucleic acid clone of hepatitis E virus and an assay system for rapid anti-HEV drug testing. |
| priorityDate | 2000-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 442.