http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1166122-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2b1c4d5cfdd1e2c6e5a98d3f9a97c4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_515d8c389673c8488e1ae0ea92a555a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b67bf0ac9b6eea44d10ca96a2f5d09a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49b8bb9c34ba2424d073b5cf5f0f10f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd617ab10e6a488f96c8b223df2b8ba1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-81 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6887 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2000-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f173f0232b90914d06989cfc804c8e4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7bd0ebad4e53944bb646506a8592b28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acda2bb814e1073cbb15f829950fbc3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a95c7f8be0d789e223ccb5d25541650 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2287609edb84ccc3e27befafc99f8fa2 |
| publicationDate | 2002-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1166122-A1 |
| titleOfInvention | Method for prediction of bone fractures by osteocalcin measurements |
| abstract | This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention. |
| priorityDate | 1999-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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