| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9baf224a7f84a809ba33ea63af3c9a53 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2000-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6d57f4b0e5c1b849f25e69d5699f289
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fd9e2d46559bc092c490a43a690bc4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f9e3fbfe749b0df2a21e8875437a9f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_664a017fc96800754f06b800bc66cb08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e81f5534118d27c76c42064d8d144143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45e63744e6be63601d3047b3ba3e2ad4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04eb7817b697ab45cb3cf892f6be72a4 |
| publicationDate |
2001-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1157034-A1 |
| titleOfInvention |
Process for production of diphtheria toxin |
| abstract |
The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, said method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin. |
| priorityDate |
1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |