| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03f5f3efbe0f60f90890e89acd2f4f26 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2000-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_450c11f999c1d7b34e0ce5e101cf6d3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c597738f8aa09fc4450b405b6dc076f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd12a1ef2d5e0d1dfab72ce388728da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87972c186c3afbab171cc39f29340faf |
| publicationDate |
2001-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1156123-A1 |
| titleOfInvention |
Method for detecting a variation of GH1 as indicator of growth hormone dysfunction |
| abstract |
A detection method for detecting a variation in GH1 effective to act as annindicator of GH dysfunction in a patient, comprises the steps of comparing a testnsample comprising a nucleotide sequence of the human GH1 gene from the patientnwith a standard sequence known to be that of the human GH1 gene. A differencenbetween the test sample sequence and the standard sequence indicates the presence ofna variation effective to act as an indicator of GH dysfunction (hereinafter "GHnvariant"). The test sample is obtained from a patient exhibiting the followingncumulative criteria:n (i) height velocity below the 25 th centile for age; (ii) bone age delay according to the Tanner-Whitehouse scale of at least twonyears when compared with chronological age; and (iii) no other disorder known to cause inclusion in criteria (i) to (ii) above. n Also disclosed are mutations thereby detected, and their use in screeningnpatients for growth hormone irregularities or for producing variant proteins suitable forntreating such irregularities. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013113074-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9717778-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9821034-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03042408-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004057028-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03042408-A3 |
| priorityDate |
2000-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |