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filingDate 2000-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_563691ac8712a081c954e8f8331a4429
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publicationDate 2002-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1148057-A4
titleOfInvention PORPHYRIN COMPLEX SUPPORTING A NITROIMIDAZOLE
abstract A drug which is a porphyrin derivative having a nitroimidazole compound bonded thereto. It takes advantage of the affinity of the porphyrin derivative for cancers. It functions to form an image in magnetic resonance imagination (MRI) and further has a sensitizing function for radiotherapy. Also provided is a porphyrin compound which is applicable to a treatment with a DDS and is free from light toxicity. Specifically, the compound is a porphyrin complex represented by formula (I) or a pharmacologically acceptable salt thereof. [wherein R?1 and R2¿ each represents -CH=CH¿2?, -CH(CH3)OH, or -CH(CH3)O-(CH2)n-NH-R?a (Ra¿ represents hydrogen or a group represented by formula (II) and n and m each is an integer of 2 or 3); R3 represents hydrogen or -CO(CH¿2?)m-CO2H; and M represents a transition metal selected among manganese, iron, cobalt, and copper].
priorityDate 1999-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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