http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1147188-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5181f7bc41146d952cf4e72f866a39ca |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2000-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d57faaf209efcfcf40efc9a8044cb663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b2cc688263e796b608b0366f904da9f |
| publicationDate | 2007-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1147188-B1 |
| titleOfInvention | Internal ribosome entry site (ires), vector containing same and the uses thereof |
| abstract | The current invention relates to two isoforms, p110 and p58 of PITSLRE protein kinase, which can be translated from the same p110 ( alpha 2-2) mRNA by an internal ribosome entry process. This means that p110 and p58, two proteins with putative different functions, are translated from a single mRNA species by using two AUGs within the same reading frame. These two proteins share the 439 C-terminal amino acids that contain the kinase domain. The IRES in the polycistronic p110 mRNA is the first IRES completely localized in the coding region of a cellular mRNA. Moreover, it was unexpectedly found that the IRES element is cell cycle regulated. Translation of p58 occurs in the G2/M stage of the cell cycle. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012056441-A1 |
| priorityDate | 1999-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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