http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1147111-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3503285349d306e4ce761db30c3b53b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e42866d6c3cedbae517fbec85cb1a88a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-08 |
| filingDate | 2000-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bbe4684045ba118327e7839ebcb14cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b2a84708a1bf7bd3783bc5e5b818eb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26acb0b80a76322fadb388291052c12e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02db5801509516a4c273eac4f8acb546 |
| publicationDate | 2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1147111-A1 |
| titleOfInvention | Cryptate compounds and methods for diagnosis and therapy |
| abstract | The present invention relates to cryptate compounds useful as chelating agents. In particular, the present invention relates to functionalized derivatives of certain cryptate compounds. These functionalized derivatives are suitable for use in radiolabelling and similar applications. The present invention also relates to a method for diagnosis or therapy of a disease utilizing functionalized derivatives of cryptase compounds. In one embodiment, the present invention relates to a compound which is capable of being radiolabelled of general formula (I) in which n represents an integer from 2 to 4, where each R<4 >and R<5 >is independently selected from -H, CH3, COOH, NO2, CH2OH, H2PO4, HSO3, CN, C=ONH2 and CHO; X and Y are the same or different and are selected from the group of C-R, N, P and C-Z in which R represents a hydrogen or halogen atom or a hydroxyl, nitro, nitroso, amino, optionally substituted alkyl, optionally substituted aryl, optionally substituted aralkyl or cyano group, or a group of the formula -COOR', COCOOR', NH-COCH2Br, -NH-CO-CH=CH-COOR' in which R' is a hydrogen atom or alkyl group; or, W is selected from the group of NH, S and O; and Z is a functionalized linkage group which is capable of binding said compound of formula (I) to a molecular recognition unit and wherein at least one of X and Y is C-Z; or a pharmaceutically acceptable salt thereof |
| priorityDate | 1999-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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