http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1144010-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6829 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2000-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b09f9aea0a9658029a98acc269c9379 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be40e8039504d8b93f7b6a371dbbf3dd |
| publicationDate | 2007-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1144010-B1 |
| titleOfInvention | Prevention of chronic graft rejection by a combination of immunotoxins and costimulation blockers |
| abstract | The present invention provides a method of preventing chronic rejection of a transplant in a recipient, comprising administering to the recipient an immunotoxin, thereby reducing the recipient's T-cell population and administering to the recipient a costimulation blocker or a combination of costimulation blockers, thereby reducing a transplant-specific antibody response. Also provided is the method of preventing chronic rejection of a transplant in a recipient, further comprising administering an immunosuppressive agent to the recipient. The present invention also provides a method of reversing a late acute rejection of a transplant in a recipient having a transplant that has survived for a prolonged period of time using the method of preventing chronic rejection, comprising monitoring the recipient for an indicator of a delayed acute rejection response and administering to the recipient showing the indicator of the acute rejection response an immunotoxin, thereby reducing the recipient's T-cell population. |
| priorityDate | 1999-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.