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filingDate 1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb1852fbb8e7f7827875947e993d7e30
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publicationDate 2003-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1143928-B1
titleOfInvention Milling process for the production of finely milled medicinal substances
abstract The invention is an improved method of generating fine medicament powders suitable for inhalation. A fluid energy mill is used with conventional milling fluids such as air or nitrogen. The milling fluid is treated to have a controlled relative humidity of between 30% and 70%. This produces a fine medicament powder with a median particle size below 10 micrometer but with little or no amorphous content generated during milling. Scale formation in the mill chamber is also greatly reduced.
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