http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1142990-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-02013 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate | 1999-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f4d7ec8588f7c05638586de8267e0a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_940d015b005b0a23970310c80315e2de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a3bc32fc65fcb6de34a5639c22e5bb8 |
| publicationDate | 2001-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1142990-A1 |
| titleOfInvention | Process for producing transglutaminase |
| abstract | Transglutaminase having an enzymatic activity is produced by subjecting denatured transglutaminase to steps containing at least the following steps (a) and (b): (a) a step of forming an intermediate structure in structural construction for the state having the enzymatic activity in which the denatured enzyme is allowed to react in an aqueous medium under an acidic condition; and (b) a step of forming a higher-order structure in which the enzyme having the intermediate structure in the structural construction comes to have the enzymatic activity in an aqueous medium under a neutral pH region. Denatured transglutaminase produced with a recombinant microorganism can be refolded in good efficiency, and high-purity transglutaminase having substantially the same enzymatic activity as native transglutaminase, namely transglutaminase activity can be produced industrially. An intermediate product having the intermediate structure in the structural construction is also provided. |
| priorityDate | 1998-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 131.