http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1140982-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_489d43e5dc923e74f753f2e3bbc38e59 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0613 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-80 |
| filingDate | 1999-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72b6a1cfba3de7794651c302b145fde0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_722597b39caca4ffa773175f148c29a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31c1f83152c6c828a015fbd4baca218 |
| publicationDate | 2003-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1140982-B1 |
| titleOfInvention | Synthesis and recovery of aspartame involving enzymatic deformylation step |
| abstract | The invention relates to the synthesis of aspartame involving enzymatic deformylation of an N-formyl- alpha -L-aspartyl-L-phenylalanine compound by treatment with an enzyme having formylmethionyl peptide deformylase activity and having as a co-factor group 5 to 11 bivalent metal ions. The invention also relates to selective preparation and recovery of aspartame from a mixture of N-formyl- alpha - and beta -L-aspartyl-L-phenylalanine compounds by treatment with such enzyme. And finally, the invention relates to one-pot enzymatic synthesis of aspartame from N-formyl-L-aspartic acid and L- or D,L-phenylalanine methyl ester involving an enzymatic deformylation reaction simultaneously with an enzymatic coupling reaction, as well as to one-pot di- or oligopeptide synthesis by simultaneous enzymatic coupling and deformylation reactions in general. |
| priorityDate | 1998-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 729.