| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2b9dc89cc4ba060cc73bbf0c90bbb78 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/F26B5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4525 |
| filingDate |
1999-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3475e077e646945108ca42ac10d97d30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e56f94d30e0352db9f7083db24c2a66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ea14be947845165faf23fadbd26392b |
| publicationDate |
2001-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1140910-A1 |
| titleOfInvention |
Process for the preparation of an acetate salt of paroxetine or paroxetine analogues |
| abstract |
The present invention relates to a new process for the preparation of an acetate salt of a compound of formula (1) in which R1 is a substituted phenyl group, preferably 3,4-methylenedioxyphenyl; the process comprising treating a solution of the compound of formula (1) with acetic acid and a co-solvent. The (-) trans isomer of 4-(4'-fluorophenyl)-3-(3',4'-methylenedioxyphenoxymethyl)-piperidine (paroxetine) is an important compound having antidepressant and anti-Parkinson properties. This compound is used in therapy as the hydrochloride salt to treat inter alia depression obsessive compulsive disorder (OCD) and panic. |
| priorityDate |
1998-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |