| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a491edee745b74e7740822e13b5bf1c1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-307 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C23-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C23-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C23-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C23-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-307 |
| filingDate |
2000-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78e4fdcb390dc79c6e70899b2a9f5caf |
| publicationDate |
2001-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1140734-A1 |
| titleOfInvention |
Preparation of selectively fluorinated organic compounds |
| abstract |
The present invention provides a method of selectively fluorinating a carbon-hydrogen bond at an unactivated saturated sp3 hybridised carbon atom of an organic compound, the method including reacting the organic compound with elemental fluorine gas, characterised in that the reaction is carried out in the presence of a basic compound. The method enables the selective transformation of carbon-hydrogen bonds to carbon-fluorine bonds in molecules where the hydrogen atom is attached to a fully saturated unactivated sp3 hybridised carbon atom such as a tertiary carbon atom found in many saturated hydrocarbon compounds and steroid derivatives. Advantageously, the method may be carried out at or just below room temperature. |
| priorityDate |
1999-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |