http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1140211-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07addebfc9446dc5a9a77692ebf4dac1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-223 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22 |
| filingDate | 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c7018364ffa5dea05402927bcf94421 |
| publicationDate | 2001-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1140211-A1 |
| titleOfInvention | Novel ultrasound contrast agents |
| abstract | New and structurally distinct ultrasound contrast agents that comprise micron size microbubbles encapsulating a gas within a shell made from a blend of bipolar compounds having inter-molecular hydrophobic regions of mixed carbon chain length. The compounds have the following structure: R1-X-Z; R2-X-Z; and R3-X-Z', where R1, R2 and R3 are hydrophobic groups selected from the group consisting of straight-chained alkyls, alkylethers, alkylthiolethers, alkyldisulfides, polyfluoroalkyls, and polyfluoroalkylethers having a carbon chain length greater than or equal to 16 and less than or equal to 32 and where R1 is greater than R2 and R1 is greater than or equal to R3; R3 has one or more such hydrophobic groups having the same or different lengths; X is a linker connecting the hydrophobic group to the polar head group; Z is a polar head group selected from the group consisting of CO2-M+, SO3-M+, SO4-M+, PO3-M+, PO4-M+2, N(R)4+, a pyridinium or substituted pyridinium group, and a zwitterionic group; R is selected from the group consisting of -H, -CH¿3?, alkyl, cycloalkyl, substituted cycloalkyls containing one or more heteroatoms, and benzyl and can be the same or different; and Z' is a nonionic group. |
| priorityDate | 1998-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 275.