Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-56 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 |
filingDate |
1999-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1477c5e401b2b494594d6a7d5e061245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25f5cbaaf635492f60af8b51a1825223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9df87afbf020eff345ab797f8761f967 |
publicationDate |
2006-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1137663-B1 |
titleOfInvention |
Purification of echinocandin cyclopeptide compounds |
abstract |
A method is described for separating and purifying a wide variety of fermentation cyclopeptide products containing at least one protonatable amino group (including the deacylated Echinocandin-type compounds) from their fermentation or mixed broths and partially purified process streams by adsorbing the mixture onto a hydrophobic, reversed phase chromatographic media and eluting with a continuous linear acetic acid gradient ranging from 0.1% acetic acid to 10.0% acetic acid by volume in water. A process for removing tripeptide-aldehyde by-products from the fermentation products by means of a derivatizing agent is also described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8927690-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012041218-A1 |
priorityDate |
1998-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |