http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1131110-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-106
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00
filingDate 1999-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bad8840c38861afd210bec41df3074ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_748da9d7978659cff028d0c0ff2ea73c
publicationDate 2001-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1131110-A1
titleOfInvention Stabilised protein preparations for a tissue adhesive
abstract A tissue adhesive is described, which contains three separate components, i.e.,a stabilized, essentially fibrinogen-free protein preparation that is of storage-quality in liquid state and contains the blood coagulation factor XIIIa stabilized protein preparation that is of storage-quality in liquid state and contains fibrinogen. A chaotropic substance of less than 0.28 mol/liter was added to said protein preparation to avoid or reduce the aggregation of fibrinogen, anda preparation containing thrombin,which are provided in one packaging unit prepared to be used together.Furthermore, stabilized, frozen or lyophilized protein preparations containing fibrinogen and Factor XIII are described. Said protein preparations contain fibrinogen- and Factor XIII which remains stable for more than four weeks after defrosting or reconstitution, as well as one or more added chaotropic substances in a quantity of less than 0.28 mol/liter which prevents or reduces the aggregation of fibrinogen and contain inorganic salts of <100 mmol/liter, preferably <50 mmol/liter.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10391062-B2
priorityDate 1998-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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