abstract |
The invention provides a method of recombining a plurality of parentalnnucleic acids, comprising:n hybridizing a library of oligonucleotides, synthesized to correspond to anplurality of parental nucleic acids, to at least one template nucleic acid; extending the hybridized library of oligonucleotides with a polymerase; and, ligating the resulting extended oligonucleotides with a ligase, therebynproducing a recombinant nucleic acid. |