| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9259cfa966fe620251340a003f5d6125 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-968
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
1999-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aec82285553ea7af2944ff63607bb50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13fa817cd3184c4d284108c7418e19e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b68484113ad1845aa7031ddff0da43c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37104cf515d192828c0672de358097cd |
| publicationDate |
2005-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1129355-B1 |
| titleOfInvention |
Use of radioligands to screen inhibitors of amyloid-beta peptide production |
| abstract |
This invention relates to a novel method of screening for inhibitors of beta-amyloid production, and thereby identifying such inhibitors as therapeutics for neurological and other disorders involving APP processing and beta-amyloid production. This invention also relates to identifying macromolecules involved in APP processing and beta-amyloid production. Furthermore, inhibitors identified by the screening method of the present invention are useful in the treatment of neurological disorders, such as Alzheimer's disease, which involve elevated levels of Abeta peptides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7906625-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8414893-B2 |
| priorityDate |
1998-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |