| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_299cff96bb72ae26b6cfe2d849f81bc9 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate |
1999-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1a4af4b0e7944965faa350d6aa94703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bb2429d081f4c9a91babf4d17cd2c82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77c96436cda629bec1f55cac4a79c2e6 |
| publicationDate |
2005-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1125924-B1 |
| titleOfInvention |
Intermediate for the synthesis of amlodipine, preparation process and corresponding utilization |
| abstract |
An intermediate for the synthesis of amlodipine, a process for the preparation thereof and the corresponding use are disclosed. The intermediate is ethyl 3-amino-4-(2-(phthalimido)ethoxy)crotonate and is of formula III <CHEM> The process for the preparation thereof comprises reacting the acetoacetate of formula <CHEM> with ammonium acetate; and the use thereof is for the preparation of the compound of formula <CHEM> the process being conducted by reacting ethyl 3-amino-4-Ä2-(phthalimido)ethoxyÜcrotonate with a benzylidene derivative. |
| priorityDate |
1998-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |