| abstract |
This invention relates to the use of estrogen agonists / antagonists for thenmanufacture of medicaments for the treatment of conditions that are responsive tonthe elevation of testosterone levels in the body. The compositions are comprised ofnan estrogen agonist / antagonist and a pharmaceutically acceptable vehicle, carriernor diluent. These compositions are effective in treating male subject sexualndysfunction and timidity in female subjects including post-menopausal women andnare effective in increasing libido in female subjects including post-menopausalnwomen. In the case of male subject sexual dysfunction, the compositions may alsoninclude a compound which is an elevator of cyclic guanosine 3',5'-monophosphaten(cGMP). Additionally, the compositions are effective in other conditions whosenetiology is a result of testosterone deficiency or which can be ameliorated bynincreasing testosterone levels within the body. Uses according to the inventionninclude the treatment of conditions that are responsive to elevation of testosteronenlevels such as treating male subject sexual dysfunction and timidity in femalensubjects including post-menopausal women and the increase of libido of femalensubjects including post-menopausal women. The uses according to the inventionnare effective while substantially reducing the concomitant liability of adverse effectsnassociated with testosterone administration. |