http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1125130-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fd30195869a178004caf2d82382034d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-205 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56922 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-121 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
| filingDate | 1999-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7201b9b61478fbbaab977faab292026d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6711374c927e71bd8f61454a1c74bc35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fee2a53bb33df7cbf652df511927ac5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_336029c5d933c00e48268775e52697c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43dfe77b5c4249cc59bbf27d6717f882 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2993d36f9f42279c49c23c534fb251bd |
| publicationDate | 2006-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1125130-B1 |
| titleOfInvention | Detection of acid-resistant micro-organisms in a stool |
| abstract | Infection of mammals by an acid-resistant microorganism (A) is detected by treating a fecal sample with at least two different monoclonal antibodies (MAb) (or their fragments or derivatives) or aptamers (collectively (I)) and detecting formation of a complex (C) between (I) and the corresponding antigen of (A). Infection of mammals by an acid-resistant microorganism (A) is detected by treating a fecal sample with at least two different monoclonal antibodies (MAb) (or their fragments or derivatives) or aptamers (collectively (I)) and detecting formation of a complex (C) between (I) and the corresponding antigen of (A). The first and second (I) bind to epitopes of different antigens (Ag). These epitopes are present, after passage through the intestines, in at least some mammals, and have either: (i) their native structure; or (ii) a structure against which an antibody is produced by an animal infected or immunized with (A), or its extract, lysate, derived protein or fragment, or with a synthetic peptide. Practically all mammals display at least one of the specified epitopes. Independent claims are also included for the following: (1) MAb, or their fragments or derivatives, that bind a variable (V) region consisting of specified CDRs (complementarity determining regions) or produced by particular hybridomas; (2) aptamers that bind to the same antigens as MAb of (a); (3) epitopes that are specifically bound by (a) or (b); (4) antibodies (or fragments or derivatives) that bind to (c); (5) diagnostic composition containing at least two (I), optionally fixed to a carrier; (6) test device for detecting epitopes of (c); (7) kits containing at least two (I), optionally immobilized, a device for processing a fecal sample and optionally a mixture of at least two (I); (8) composition, particularly a pharmaceutical, containing at least one (I), optionally also a carrier and/or diluent; and (9) package containing (e)-(g). ACTIVITY : Antibacterial. MECHANISM OF ACTION : None given. |
| priorityDate | 1998-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 473.