| abstract |
Described herein are adjuvants containing as the activeningredient an attenuated toxin having a residual activity of atnleast 1/2000 the activity of the natural toxin and vaccinesncontaining such adjuvants. By using, for example, attenuatednnatural cholera toxin, vaccines capable of showing sufficientnimmune potentiation in percutaneous vaccination or nasalnvaccination can be presented. |