http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1121458-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8787b4aa2ca77c2884a8d7baed1e4221 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate | 1999-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3708238f8c8aa19d117af5408cc6b6cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74a8992ea362b93933117e5a7840a982 |
| publicationDate | 2001-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1121458-A1 |
| titleOfInvention | Methods for assessing complement activation |
| abstract | Methods for measuring in vivo activation of the lectin pathway by measuring mannan-binding serine protease activity (MASP) are provided. The methods are accomplished by measuring C3a and C4a levels in in vitro activated EDTA plasma. In particular, the increase in C3a and/or C4a as a function of time is an indicator of the amount of activated MASP in EDTA plasma. Methods are also provided for measuring the alternate and classical pathways of complement activation, exclusive of the lectin pathway, and thereby disorders associated therewith. To perform such measurements, Futhan or other serine protease inhibitor is added to blood or plasma, containing a divalent metal ion chelator, and C3a and C4a are measured. |
| priorityDate | 1998-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.