abstract |
Compounds having formula (I) and pharmaceutically acceptablensalts thereof, wherein B is NR 5 R 11 , wherein R 5 is selectednfrom the group consisting of hydrogen, lower alkyl, lowernalkenyl, lower alkynyl and aryl, and R 11 is selected from an3 to 8 member heterocyclyl radical in which at least one membernof the ring is carbon and in which 1 to about 4 membersnare heteroatoms independently selected from oxygen, nitrogennand sulfur and said heterocyclyl radical may be optionallynsubstituted, useful as nitric oxide synthase inhibitors. |