| abstract |
The present invention relates to the use as an active substance of molecules binding to β1-integrins and with the capacity to kill cells having β1-integrins for production of pharmaceuticals for treatment of conditions dependent on cells having β1-integrins such as cancer and conditions dependent on T lymphocytes and fibrotic conditions. Especially the invention relates to the use of Invasin (Inv) from Yersinia (Yer) species, subfragments, variants, and peptides thereof, microorganisms producing invasin and invasin like substances and antibodies binding β1-integrins and with the capacity to kill cells having β1-integrins. |