| abstract |
Amyloid binding compounds which are derivatives of Chrysamine G,npharmaceutical compositions containing, and methods using such compounds tonidentify Alzheimer's brain in vivo and to diagnose other pathological conditionsncharacterized by amyloidosis, such as Down's Syndrome are described.nPharmaceutical compositions containing Chrysamine G and derivatives thereofnand methods using such compositions to prevent cell degeneration and amyloid-inducedntoxicity in amyloidosis associated conditions are also described.nMethods using Chrysamine G derivatives to stain or detect amyloid deposits innbiopsy or post-mortem tissue are also described. Methods using Chrysamine Gnderivatives to quantify amyloid deposits in homogenates of biopsy and post-mortemntissue are also described. |