http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1110943-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44c713790ce00813da2e6c6d57a29456 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D339-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D339-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-72 |
| filingDate | 1999-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53017299c7b37e7d7ec0fec17a32c5a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c099e5f571543b9573f8184923e8ea1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15777c39aa3306129b7d42e9eefb636b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58c954e8aff2d830d4133d75b05dfe0a |
| publicationDate | 2004-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1110943-B1 |
| titleOfInvention | 6-fluorobicyclo 3. 1.0]hexane derivatives |
| abstract | The present invention provides fluorobicycloÄ3.1.0Ühexane derivatives represented by the formula <CHEM> Äwherein R<1> and R<2> are the same or different and each represents a hydrogen atom, a C1-10 alkyl group, a C3-8 cycloalkyl group or a C3-8 cycloalkyl-C1-5 alkyl group: Y<1> and Y<2> are the same or different and each represents a hydrogen atom, a C1-10 alkylthio group, a C3-8 cycloalkylthio group, a C3-8 cycloalkyl-C1-5 alkylthio group, a C1-5 alkoxy group, a C3-8 cycloalkoxy group or a C3-8 cycloalkyl-C1-5 alkoxy group; or one represents a hydrogen atom and the other represents a hydroxyl group, a C1-5 alkoxy group, a C3-8 cycloalkoxy group or a C3-8 cycloalkyl-C1-5 alkoxy group; or Y<1> and Y<2> together represent an oxygen atom or -X(CH2)nX- (X represents an oxygen atom or a sulfur atom: n is 2 or 3) Ü, pharmaceutically acceptable salts thereof, or hydrates thereof. The compounds of the present invention are useful as drugs, in particular group 2 metabotropic glutamate receptor agonists, and useful for treatment or prevention of psychiatric disorders such as, for example, schizophrenia, anxiety and associated diseases, depression, bipolar disorder, and epilepsy, as well as neurological diseases such as, for example, drug dependence, cognitive disorders, Alzheimer's disease, Huntington's chorea, Parkinson's disease, dyskinesia associated with muscular stiffness, cerebral ischemia, cerebral failure, myelopathy, and head trauma. |
| priorityDate | 1998-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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