abstract |
This invention is directed to methods, pharmaceutical compositions and kitsncomprising an aldose reductase inhibitor (ARI), a prodrug thereof or anpharmaceutically acceptablre salt of said ARI or said prodrug and annantihypertensive agent, a prodrug thereof or a pharmaceutically acceptable salt ofnsaid antihypertensive agent or said prodrug. This invention further relates to methodsnof using those pharmaceutical compositions for the treatment of diabeticncomplications such as diabetic neuropathy, diabetic nephropathy, diabeticnretinopathy, myocardial infarction, cataracts and diabetic cardiomyopathy. |