| abstract |
This invention is directed to methods, pharmaceutical compositions and kitsncomprising an aldose reductase inhibitor (ARI), a prodrug thereof or anpharmaceutically acceptable salt of said ARI or said prodrug and selective serotoninnreuptake inhibitor (SSRI), a prodrug thereof or a pharmaceutically acceptable salt ofnsaid SSRI or said prodrug. This invention further relates to methods of using thosenpharmaceutical compositions for the treatment of diabetic complications such asndiabetic neuropathy, diabetic nephropathy, diabetic retinopathy, myocardial infarction,ncataracts and diabetic cardiomyopathy. |