| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d779d73c301192ffbaf00434e582a534 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M47-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
1990-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_171502488377e8cd7eb07464eac8cd5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a181f626645339a7dfa3434d4fe8d3d |
| publicationDate |
2001-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1104807-A2 |
| titleOfInvention |
Apparatus for the production of TGF-beta |
| abstract |
Transforming growth factor β (TGF-β) isnproduced in relatively large quantities and at anrelatively high purity by fermentation in a perfusionnmicrocarrier reactor. Conditioned media from the reactornis first treated to provide the active form of TGF-β andnsubsequently purified by cation exchange chromatographynfollowed by hydrophobic interaction chromatography.nOptionally, nucleic acids complexed with the TGF-β may benremoved while the protein is bound to the cation exchangenresin. Purified TGF-βI compositions have a specificnactivity above 10 7 U/ml. |
| priorityDate |
1989-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |