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publicationDate 2001-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1104492-A1
titleOfInvention Subtle mitochondrial mutations as tumor markers
abstract The accumulation of homoplasmic somatic mutations has been observed in the mitochondrial DNA of certain tumor cells. The presence or recurrence of a tumor can be detected by determining the presence of single basepair mutations in the mitochondrial genome from a cell sample of a patient.
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