abstract |
The present invention is directed to novel carboxylic acids and isosteres of heterocyclic ring compounds of formula (I) which have multiple heteroatoms within the heterocyclic ring, novel derivatives containing N-linked diketos, sulfonamides, ureas and carbamates attached thereto, their preparation and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, as well as for treating alopecia and promoting hair growth. A, X, Y, Z, D and n are as defined in the application. |