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filingDate 2000-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2001-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1101438-A1
titleOfInvention Method and apparatus for acquiring fluorescence images
abstract Intrinsic fluorescence, which has been produced fromnliving body tissues when excitation light is irradiated to thenliving body tissues, is detected with an image sensor and isnread out as an image. The image is acquired by setting the imagensensor such that a reading frequency, an area of one pixel,na total number of pixels, a number of pixels subjected to pixelnbinning, a number of reading ports, an exposure time, a quantumnefficiency, an electron multiplication factor, and a sensorntemperature of the image sensor satisfy the following conditionnformula:n RN+DN<0.22×P×H×G nin which RN represents the number of electric charges occurringndue to reading noise, DN represents the number of electricncharges occurring due to dark noise, P represents thenirradiation output of the excitation light (in mW), H representsnthe quantum efficiency of the image sensor, and G representsnthe electron multiplication factor of the image sensor.
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