abstract |
Damage to cells, tissue and other body parts in a mammalian host may be treated by using hypoxanthine and in conjunction with at least one biological modifier, which may be a free radical scavenger or a metabolic inhibitor. The biological modifier is preferably uric acid, buthionine sulphoximine, vitamin C, aspirin, or nordihydroguaiaretic acid. Such a combination may be used to treat, for example, cancer, infectious diseases, neurodegenerative disease and damage caused by radiation therapy, high oxygen tension, and chemotherapy. |