abstract |
Chymase inhibitors and cytokine production inhibitors containing compounds represented by general formula (I), prodrugs of thensame, pharmaceutically acceptable salts thereof or hydrates of them, wherein A is -CO-, -CONH- or the like; R 1 is optionally substitutednlower alkyl, optionally substituted aryl or the like; R 2 and R 3 are each independently hydrogen, optionally substituted lower alkyl or the like;nB is -S-, -O- or the like; and R 4 is optionally substituted aryl or the like. |