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filingDate 1999-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f88c510eb100176d0c22dd24b6be8670
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publicationDate 2001-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1095160-A1
titleOfInvention Method for producing (1r,4s)-2-azabicyclo 2.2.1 hept-5-en-3-on derivatives.
abstract A biotechnological method is described for preparing compounds of the general formulas wherein R<1 >is acyl or acyloxy and R<2 >is a hydrogen atom or C1-10 alkyl, comprising the conversion of a lactam of the general formula by means of a hydrolase in the presence of a nucleophile and in the presence of a base in a constant pH range. Also described is the subsequent conversion of the compound of general formula I into the optically active 1-amino-4-(hydroxymethyl)-2-cyclopentene of the formula
priorityDate 1998-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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