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filingDate 2000-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bec1cbefeb41b8b759607fb8182c9545
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publicationDate 2001-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1092978-A1
titleOfInvention Method and device for determining the concentration of heparin in a sample of fluid
abstract A method for determining the concentration of heparin in anfluid sample comprising: (a) providing a fluid samplencontaining heparin; (b) adding to the fluid sample ansolution of a dye to form a mixture of sample and dye,nwherein the dye interacts with the heparin in the sample sonthat the absorption spectrum of the mixture of sample andndye in the visible range varies as a result of theninteraction in a manner quantitatively dependent on thenheparin concentration; (c) determining the absorptionnspectrum in the visible range of the mixture of sample andndye; and (d) calculating a spectral parameter representativenof both the reduction in the absorption of the free dye innsolution and the increase in the absorption of the dye-heparinncomplex, the value of the spectral parameter beingnindicative of the concentration of heparin present in thenfluid sample, in order to determine the concentration ofnheparin present in the fluid sample.
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priorityDate 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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