http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1090279-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34b960493fcb355a6ecbc26ce85de084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d02e8dcfcaa02221861929d6e6aec78a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-904 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 |
| filingDate | 1999-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271829171d6b2c9f0c00a44850911bc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a12efcdc85e28140887b9f077835a81f |
| publicationDate | 2001-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1090279-A2 |
| titleOfInvention | Screening method for dehydrogenase oligomerisation modulators |
| abstract | Methods of screening compounds which are oligomeric modulators of dehydrogenases such as glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and such oligomeric modulators. In one aspect, methods are presented for identifying an oligomeric modulator of a dehydrogenase, comprising contacting the dehydrogenase with a compound under conditions which allow oligomerization of the dehydrogenase to occur; and measuring the ability of the compound to modulate oligomerization of the dehydrogenase as an indication of whether the compound is an oligomeric modulator of the dehydrogenase. In another aspect, methods are presented for identifying an oligomeric modulator of GAPDH, comprising contacting GAPDH with a compound under conditions which allow oligomerization of GAPDH to occur; and measuring the ability of the compound to modulate oligomerization of GAPDH as an indication of whether the compound is an oligomeric modulator of GAPDH. In another aspect, methods are presented for identifying antiapoptotic agents, comprising contacting GAPDH with a compound under conditions which allow oligomerization of GAPDH to occur; and measuring the ability of the compound to modulate oligomerization of GAPDH as an indication of whether the compound is an antiapoptotic agent. |
| priorityDate | 1998-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 419.