Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3873abaff397acbfffa1595a12cfef41 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3341 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-09 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
1999-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c306b961e04757eb82650467f07a2f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a40d9284b7112d9eeae595ebf00c46a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36390515959c8e90d688c5231fdb8972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_467221d96a174004662de4c04fd004a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2df9a5bbd88df4806eeaeaad94f1128d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adcfc9c2a5490d50515e124bb169a841 |
publicationDate |
2006-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1088066-B1 |
titleOfInvention |
Antisense oligonucleotide constructs based on beta-arabinofuranose and its analogues |
abstract |
The present invention relates to modified oligonucleotide therapeutic agents to selectively prevent gene transcription and expression in a sequence-specific manner. In particular, this invention relates to the selective inhibition of protein biosynthesis via antisense strategy using oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues. More particularly this invention relates to the use of antisense oligonucleotides having arabinose sugars to hybridize to complementary RNA such as cellular messenger RNA, viral RNA, etc. |
priorityDate |
1998-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |