http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1086179-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a234c1c464269b0e3a859b05c56e8731 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-968 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B23-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 |
| filingDate | 1999-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cd40fca487d1de4d066c58600c0a2f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_930ed9feeef209e1774d4361a0cde2a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4099817cbf1e19497c087ce846e2049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3859e6ff698fdb78997e9b27c8c266ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2824434c61011c583884d109d4b97b56 |
| publicationDate | 2001-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1086179-A1 |
| titleOfInvention | Energy transfer assay method and reagent |
| abstract | Disclosed is a non-fluorescent cyanine dye that may be used as an acceptor in fluorescence energy transfer assays involving the detection of binding and/or cleavage events in reactions involving biological molecules, and assay methods utilising such dyes. The non-fluorescent cyanine dye is a compound of formula (I), wherein the linker group Q contains at least one double bond and forms a conjugated system with the rings containing X and Y; groups R<3>, R<4>, R<5 >and R<6 >are attached to the rings containing X and Y, or optionally, are attached to atoms of the Z<1 >and Z<2 >ring structures; Z<1 >and Z<2 >each represent a bond or the atoms necessary to complete one or two fused aromatic rings each ring having five or six atoms, selected from carbon atoms and, optionally, no more than two oxygen, nitrogen and sulphur atoms; at least one of groups R<1>, R<2>, R<3>, R<4>, R<5>, R<6>and R<7 >is a target bonding group; any remaining groups R<3>, R<4>, R<5>, R<6 >and R<7 >groups are independently selected from the group consisting of hydrogen, C1-C4 alkyl, OR<9>, COOR<9>, nitro, amino, acylamino, quaternary ammonium, phosphate sulphonate and sulphate, where R<9 >is selected from H and C1-C4 alkyl; any remaining R<1 >and R<2 >are selected from C1-C10 alkyl which may be unsubstituted or substituted with phenyl, the phenyl being optionally substituted by up to two substituents selected from carboxyl, sulphonate and nitro groups; characterised in that at least one of the groups R<1>, R<2>, R<3>, R<4>, R<5>, R<6 >and R<7 >comprises a substituent which reduces the fluorescence emission of said dye such that it is essentially non-fluorescent. |
| priorityDate | 1998-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 229.