| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8dfe398c73a50de2734113f38cc5125 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00668
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00317
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00319
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00286
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00461
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00527
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B60-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0819 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B60-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L99-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B60-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 |
| filingDate |
1999-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_687f5cfaecd1ae87c42b1fc172cc0e48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb46c9e496ebddd384ba074955b639bb |
| publicationDate |
2006-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1085943-A4 |
| titleOfInvention |
THREE-DIMENSIONAL SUBSTRATE MATRIX FOR SOLID PHASE PARALLEL SYNTHESIS AND APPLICATION METHOD |
| abstract |
A three-dimensional (3D) array of solid-phase supports is adapted to provide parallel synthesis of a library of molecules with 3D diversity. Individual locations in the 3D array may be assigned to selected molecules in the library such that molecules may be synthesized at and retrieved from such locations. Also, the supports include aperture walls in stacked plates; the supports may be suspended within stacked plate apertures; the 3D array includes discrete supports arranged in columns in one or more wells; the supports include tube inner walls or may be suspended in tubes, the tubes being secured in stacked, two-dimensional (2D) frameworks; or the supports include beads contained in porous enclosures having non-porous side walls and being secured in stacked, 2D frameworks. A support transfer device enables transfer of solid-phase supports used in a 3D array. Such apparatus includes: a rack of rods sized to be inserted through supports and a mechanism to prevent supports from coming off the rack; tubes connected to a vacuum manifold to suction supports one Z plane at a time; or a transfer block having recesses to receive one or more supports and at least one gate withholding supports from passing through the gate when in a closed position. A method of 3D synthesis includes: a) functionalizing solid-phase supports; b) placing supports in a 3D array; and c) performing parallel synthesis with 3D diversity. At least one unique R1 group member may be assigned to each Z plane. |
| priorityDate |
1998-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |