Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4291 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-74 |
filingDate |
1999-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ad5c54556d9c0039c482ea28fb481ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ef9805b2b82bfff4a09ceede4652656 |
publicationDate |
2001-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1084136-A1 |
titleOfInvention |
Separation of protein monomers from aggregates by use of ion-exchange chromatography |
abstract |
The invention relates to a method for separating a mammalian polypeptide monomer from a mixture comprising monomers of said polypeptide and dimers of said polypeptide or multimers (n-mers of said polypeptide where n is 3-10) or both. The method comprises the step of applying the mixture to a cation-exchange or anion-exchange chromatography resin and eluting the mixture with a gradient of about 0-1 M of an elution salt. Thereby the monomer is separated from the dimers or multimers or both present in the mixture. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008145351-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2261252-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012123488-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11034754-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9631007-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9631008-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006125599-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010072381-A1 |
priorityDate |
1998-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |